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Natural Plant-Based Antimicrobial Agent via Nano emulsion-Based Technologies

The invention is plant based nano emulsion solution, a novel non-toxic germicide agent against methicillin-resistant
Staphylococcus aureus (MRSA) and Acinetobacter baumannii infection, which is a common threat to public health but with
limited therapeutic options.

The formulation is also effective in killing viruses including human coronavirus OC43 (hCoV-OC43) in
vitro which is a beta coronavirus under the same group as the SARS-CoV-2. It also exhibited good antioxidant properties. Thus,
making the invention as unique which be used as dual therapy in managing the infections.

COVID-19 patients admitted in ICUs are coinfected and superinfected with multidrug resistance bacteria such as
Acetinobacter baumii. Recent study also found that more than 25% of all co-infections in COVID-19 patients were related to
Staphylococcus aureus (S. aureus), more than half of which were MRSA.

Current challenge in treating MRSA and multidrug resistance Acinetobacter baumannii (MDRAB)

Resistant to biocides or disinfectants in the hospital settings has been a global issue. Several biocide resistance genes have ben
detected including FabL gene in these isolates. More importantly, the presence of different resistance genes (biocide
and antibiotics) would encourage their combination into the same genetic element (plasmids and integrons) which can then
be transmitted between species via horizontal gene transfer. 

Creation of New Business.

• The product is an eco-friendly hand sanitizer, antiseptic and hospital decontaminant agent.
• The product is made from natural resources which are effective, biodegradable, low cost and affordable.

The formulation can be effectively used as a natural, green and eco-friendly germicide agent for medical application, it will open the door for many business opportunities mainly in the pharmaceutical
industry.

 

Project Leader : Dr. Nur Kartinee Kassim
Dept./Faculty : Chemistry, Faculty of Science
Email : kartinee@upm.edu.my

Tarikh Input: 23/02/2022 | Kemaskini: 23/02/2022 | asrizam

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Selangor Darul Ehsan
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